fibroblast growth factor 23 ifgf23  (Quidel)

Journal: The Journal of Investigative Dermatology

Article Title: GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification

doi: 10.1016/j.jid.2023.09.008

Figure Lengend Snippet: FGF23 (intact molecule and C-terminal) correlation to 1,25-hydroxy vitamin D, serum calcium corrected to albumin and serum phosphate. Note the opposite relationships between 1,25-hydroxyvitamin D and C-terminal FGF23 and its biologically active form intact FGF23. ( a and b ) Correlation between intact and C-terminal FGF23 and 1,25-hydroxyvitamin D. ( c and d ) Correlation between intact and C-terminal FGF23 and albumin-corrected serum calcium. ( e and f ) Correlation between intact and C-terminal FGF23 and serum phosphate. Statistical correlations were performed in Prism as detailed in the methods. FGF23, fibroblast growth factor 23; 1,25OH, 1,25-hydroxy.

Article Snippet: Blood indices measured were ionized calcium, total calcium, phosphate, magnesium, PTH, alkaline phosphatase, FGF23, both C-terminal fibroblast growth factor 23 and iFGF23 (Immutopics), 1,25-dihydroxyvitamin D, 25-hydroxy-vitamin D, urea, and electrolytes.

Techniques:

Journal: The Journal of Investigative Dermatology

Article Title: GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification

doi: 10.1016/j.jid.2023.09.008

Figure Lengend Snippet: Calcium homeostatic relationships governed by the parathyroid and kidney behave normally in the GNAQ/GNA11 mosaic cohort. ( a ) Significant inverse correlation between serum calcium corrected to albumin and serum PTH. ( b ) Significant correlation between serum calcium corrected to albumin and urine calcium/creatinine ratio. ( c ) Significant correlation between 1,25-hydroxyvitamin D and intact FGF23. ( d ) Correlation between 1,25-hydroxyvitamin D and PTH. Statistical correlations were performed in Prism as detailed in the methods. FGF23, fibroblast growth factor 23; 1,25OH, 1,25-hydroxy; PTH, parathyroid hormone.

Article Snippet: Blood indices measured were ionized calcium, total calcium, phosphate, magnesium, PTH, alkaline phosphatase, FGF23, both C-terminal fibroblast growth factor 23 and iFGF23 (Immutopics), 1,25-dihydroxyvitamin D, 25-hydroxy-vitamin D, urea, and electrolytes.

Techniques:

Journal: Nutrients

Article Title: Postprandial Metabolic Response to Rapeseed Protein in Healthy Subjects

doi: 10.3390/nu12082270

Figure Lengend Snippet: Characteristics of study participants at baseline.

Article Snippet: Plasma concentrations of interleukin-6 (IL-6) (IBL International GmbH, Hamburg, Germany), insulin (DRG Instruments GmbH, Marburg, Germany), parathyroid hormone (PTH) (Immutopics Inc, San Clemente, CA, USA), intact fibroblast growth factor-23 (iFGF23) (Immutopics Inc), and high-sensitivity C-reactive protein (hs-CRP) (IBL International GmbH) were analyzed by the use of commercially available ELISAs according to manufacturer’s protocol.

Techniques:

Journal: Nutrients

Article Title: Postprandial Metabolic Response to Rapeseed Protein in Healthy Subjects

doi: 10.3390/nu12082270

Figure Lengend Snippet: Postprandial response of the test meal (TM) with either no additional protein as reference (□), 28 g rapeseed protein isolate (RPI) (♦), or 28 g soy protein isolate (SPI) ( ▲ ) with regard to plasma calcium ( A ), inorganic phosphate ( B ), PTH ( C ), iFGF23 ( D ), zinc ( E ), and copper ( F ). Differences in mineral and related hormone concentrations after the ingestion of the three test meals over 6 h were evaluated with a mixed model to test the effects of treatment, time, and their interaction (treatment × time) on each parameter. The value at baseline (before treatment) was considered a covariate. All p values were adjusted according to the Tukey–Kramer multiple group comparison procedure. For time-point analysis, the paired t-test was applied. Significance was accepted as p < 0.05. Data are presented as LSMs ± SEs ( n = 19); iFGF23, intact fibroblast growth factor; PTH, parathyroid hormone.

Article Snippet: Plasma concentrations of interleukin-6 (IL-6) (IBL International GmbH, Hamburg, Germany), insulin (DRG Instruments GmbH, Marburg, Germany), parathyroid hormone (PTH) (Immutopics Inc, San Clemente, CA, USA), intact fibroblast growth factor-23 (iFGF23) (Immutopics Inc), and high-sensitivity C-reactive protein (hs-CRP) (IBL International GmbH) were analyzed by the use of commercially available ELISAs according to manufacturer’s protocol.

Techniques: Clinical Proteomics, Comparison

Journal: Disease Markers

Article Title: Severity of Vitamin D Deficiency Predicts Mortality in Ischemic Stroke Patients

doi: 10.1155/2019/3652894

Figure Lengend Snippet: Patients' characteristics and comparison of groups with three main stroke types.

Article Snippet: We measured serum intact fibroblast growth factor 23 (iFGF23) (Immutopics, San Clemente, CA, U.S.) and high-sensitivity (limit of quantification (0.09 mg/L) C-reactive protein (Immundiagnostik AG, Bensheim, Germany) concentrations by ELISA.

Techniques: Comparison, Modification, Filtration

Journal: Disease Markers

Article Title: Severity of Vitamin D Deficiency Predicts Mortality in Ischemic Stroke Patients

doi: 10.1155/2019/3652894

Figure Lengend Snippet: Comparison of subgroups distinguished according to the modified Rankin scale at discharge.

Article Snippet: We measured serum intact fibroblast growth factor 23 (iFGF23) (Immutopics, San Clemente, CA, U.S.) and high-sensitivity (limit of quantification (0.09 mg/L) C-reactive protein (Immundiagnostik AG, Bensheim, Germany) concentrations by ELISA.

Techniques: Comparison, Modification, Filtration

Journal: Disease Markers

Article Title: Severity of Vitamin D Deficiency Predicts Mortality in Ischemic Stroke Patients

doi: 10.1155/2019/3652894

Figure Lengend Snippet: Results of crude and age-adjusted univariable Cox proportional hazard regression for death.

Article Snippet: We measured serum intact fibroblast growth factor 23 (iFGF23) (Immutopics, San Clemente, CA, U.S.) and high-sensitivity (limit of quantification (0.09 mg/L) C-reactive protein (Immundiagnostik AG, Bensheim, Germany) concentrations by ELISA.

Techniques: Modification

Journal: Disease Markers

Article Title: Severity of Vitamin D Deficiency Predicts Mortality in Ischemic Stroke Patients

doi: 10.1155/2019/3652894

Figure Lengend Snippet: Results of crude and age-adjusted univariable Cox proportional hazard regression for composite end point.

Article Snippet: We measured serum intact fibroblast growth factor 23 (iFGF23) (Immutopics, San Clemente, CA, U.S.) and high-sensitivity (limit of quantification (0.09 mg/L) C-reactive protein (Immundiagnostik AG, Bensheim, Germany) concentrations by ELISA.

Techniques: Modification